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Product Name
Human ALK-7 / ACVR1C (Fc Tag) recombinant protein
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Description
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
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Protein name
Activin receptor type-1C
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Protein short names
ALK-7; ACTIVIN RECEPTOR TYPE IC; C230097P10; ALK7; ACTIVIN RECEPTOR TYPE-1C; ACTR-IC; ACVRLK7; RP23-100B18.1; ACTIVIN RECEPTOR-LIKE KINASE 7
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Uniprot ID
Q8NER5
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Gene Name
ACVR1C; ALK7
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ACVR1C (NP_660302.2) (Met1-Glu113) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ACVR1C consists 330 amino acids and predicts a molecular mass of 36.6 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
ACVR1C protein SDS-PAGE
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