• Amyloid β-Protein (29-40) peptide

Amyloid β-Protein (29-40) peptide

Not For Human Use, Lab Use Only.

Cat.#: 307946

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Optional Service: TFA RemovalWhat's this?

Special Price 151.8 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Amyloid β-Protein (29-40) peptide
  • Documents
  • Sequence Shortening
    GAIIGLMVGGVV
  • Sequence
    Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
  • Length (aa)
    12
  • Peptide Purity (HPLC)
    96.3%
  • Molecular Formula
    C49H88N12O13S
  • Molecular Weight
    1085.4
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Aβ 29-40, a C-terminal fragment of predominant Aβ 1-40, has physicochemical properties related to those of the fusion peptides of viral proteins. Aβ 29-40 can induce the fusion of liposomes in vitro. The apoE2 and apoE3 apolipoprotein isoforms are potent inhibitors of the fusogenic and aggregational properties of this peptide. Reciprocally this amyloid β-peptide interacts with apoE2 and apoE3 and decreases or disturbs their normal association with lipids. This domain of the amyloid β-protein could be critical for the amyloid-apoE interaction.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight

Peptide Property

  • Analysed Sequence:H-GAIIGLMVGGVV-OH
  • Chemical Formula:C49H88N12O13S
  • Sequence length:12
  • Extinction coefficient:0 M-1cm-1
  • GRAVY:2.29
  • Mw average:1085.36
  • Theoretical pI:7
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"