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Reverse Complement

Reverse Complement converts a DNA sequence into its reverse, complement, or reverse-complement counterpart. The entire IUPAC DNA alphabet is supported, and the case of each input sequence character is maintained. You may want to work with the reverse-complement of a sequence if it contains an ORF on the reverse strand.

Paste the raw sequence or one or more FASTA sequences into the text area below. Input limit is 100,000 characters.:

IUPAC codes

Symbol Bases Origin of designation
G G Guanine
A A Adenine
T T Thymine
C C Cytosine
R G or A Purine
Y T or C pyrimidine
M A or C
K G or T
S G or C Strong interaction (3 H bonds)
W A or T Weak interaction (2 H bonds)
H A or C or T not-G, H follows G in the alphabet
B G or T or C not-A, B follows A
V G or C or A not-T (not-U), V follows U
D G or A or T not-C, D follows C
N G or A or T or C aNy