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Product Name
SLC7A2 Polyclonal Antibody
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Description
Polyclonal antibody to SLC7A2
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
SLC7A2 antibody; ATRC2 antibody; CAT2 antibody; HCAT2 antibody; solute carrier family 7 member 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC7A2 (NP_001008539.3).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100 -
Validations
Western blot - SLC7A2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SLC7A2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
Immunohistochemistry - SLC7A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human mammary cancer using SLC7A2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC7A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human placenta using SLC7A2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC7A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat ovary using SLC7A2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC7A2 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse testis using SLC7A2 antibody at dilution of 1:100 (40x lens).
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Background
Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). May play a role in classical or alternative activation of macrophages via its role in arginine transport.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"