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Product Name
Human EG-VEGF / prokineticin-1 (His Tag) recombinant protein
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Description
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
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Protein name
Prokineticin-1
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Protein short names
MAMBAKINE; EG-VEGF; BLACK MAMBA TOXIN-RELATED PROTEIN; PRK1EG-VEGF; PK1; UNQ600/PRO1186; EGVEGF; PRK1; PROKINETICIN-1; ENDOCRINE-GLAND-DERIVED VASCULAR ENDOTHELIAL GROWTH FACTOR
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Uniprot ID
P58294
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Gene Name
PROK1; UNQ600/PRO1186
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human EG-VEGF (Met 1-Phe105) (P58294) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human EG-VEGF consists of 96 amino acids and predicts a molecular mass of 11 KDa. The apparent molecular mass of the protein is approximately 15 Kda in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 89 % as determined by SDS-PAGE
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Validations
Human EG-VEGF / prokineticin-1 Protein (His Tag) SDS-PAGE
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