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Product Name
Human PTH1R/PTHR1 (His Tag) recombinant protein
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Description
This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
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Protein name
Parathyroid hormone/parathyroid hormone-related peptide receptor
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Protein short names
PPR; MGC138452; PFE; PTHR; PTH1R; PTHR1; MGC138426
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Uniprot ID
Q03431
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Gene Name
PTH1R; PTHR; PTHR1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PTH1R (Q03431) extracellular domain (Met 1-Gly 188) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PTH1R consists of 173 amino acids and has a predicted molecular mass of 20 kDa. As a result of glycosylation, the apparent molecular mass of rh PTH1R is approximately 30-40 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human PTH1R / PTHR1 / PTH1 Receptor Protein (His Tag) SDS-PAGE
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