Human SIRPG/SIRPB2 (Fc tag) recombinant protein

Cat.#: 518300

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Product Information

  • Product Name
    Human SIRPG/SIRPB2 (Fc tag) recombinant protein
  • Documents
  • Description
    Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.
  • Protein name
    signal regulatory protein gamma(SIRPG)
  • Protein short names
    SIRPB2
  • Uniprot ID
    Q9P1W8
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SIRPG/SIRPB2 Glu29-Pro360 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SIRPG/SIRPB2 (Fc tag) recombinant protein

    Human SIRPG/SIRPB2 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"