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Product Name
Human HIST3H2A recombinant protein
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Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Protein name
Histone H2A type 3
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Protein short names
MGC3165; RP23-441I8.12-001
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Uniprot ID
Q7L7L0
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Gene Name
HIST3H2A
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human HIST3H2A (NP_254280.1) (Met 1-Lys 130) was expressed and purified.
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Protein Species
Human
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Molecular weight
The recombinant human HIST3H2A consists of 130 amino acids and has a calculated molecular mass of 14.2 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human HIST3H2A / Histone H2A Protein SDS-PAGE
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