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Cynomolgus HGF / Hepatocyte Growth Factor recombinant protein

Cat.#: 503008

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Product Information

  • Product Name
    Cynomolgus HGF / Hepatocyte Growth Factor recombinant protein
  • Documents
  • Description
    Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
  • Protein name
    Hepatocyte growth factor
  • Protein short names
    HGF; DFNB39; HPTA; C230052L06RIK; SF/HGF; F-TCF; SF; NK1; NK2; HGF/SF; HGFB
  • Uniprot ID
    C9E9X5
  • Gene Name
    HGF; EGM_12814
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the cynomolgus HGF (C9E9X5) (Met1-Ser728) was expressed.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant cyno HGF consists of 697 amino acids and has a calculated molecular mass of 79.6 KDa. It migrates as 89,58,34 and 32 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    (49.5+35.5+6.4+7.1) % as determined by SDS-PAGE
  • Activity
    1. Immobilized Cynomolgus HGF at 10 μg/ml (100 μl/well) can bind Cynomolgus MET-Fc (cat:502885), EC50 of Cynomolgus MET-Fc (cat:502885) is 0.04-0.09 μg/ml.
    2. Measured by its ability to inhibit TGFß1 activity on Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 2-10 ng/ml.
  • Validations

    Cynomolgus HGF / Hepatocyte Growth Factor Protein SDS-PAGE

    Cynomolgus HGF / Hepatocyte Growth Factor Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"