Human CCL22/MDC (His Tag) recombinant protein

Human CCL22/MDC (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

C-C motif chemokine 22

STCP-1; STIMULATED T CELL CHEMOTACTIC PROTEIN 1; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1); ABCD-1; CC CHEMOKINE STCP-1; ACTIVATED B AND DENDRITIC CELL-DERIVED; MEMBER 22; SMALL INDUCIBLE CYTOKINE SUBFAMILY A (CYS-CYS); MDC(1-69); MDC; A-152E5.1; C-C MOTIF CHEMOKINE 22; DC/B-CK; SMALL INDUCIBLE CYTOKINE SUBFAMILY A22; SCYA22; SMALL INDUCIBLE CYTOKINE SUBFAMILY A; DCBCK; DENDRITIC CELL AND B CELL DERIVED CHEMOKINE; CC CHEMOKINE ABCD-1; MACROPHAGE-DERIVED CHEMOKINE; SMALL-INDUCIBLE CYTOKINE A22; SMALL INDUCIBLE CYTOKINE A22

O00626

CCL22; MDC; SCYA22; A-152E5.1

E. coli

A DNA sequence encoding the secreeted form of human CCL22 (O00626) (Gly 25-Gln 93) was expressed, with a polyhistidine tag at the N-terminus.

Human

The recombinant human CCL22 consisting of 84 amino acids and has a calculated molecular mass of 9.7 KDa. It migrates as an 10 kDa band in SDS-PAGE under reducing conditions.

> 90 % as determined by SDS-PAGE