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Product Name
TNK1 Antibody (C-term)
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Description
Purified Rabbit Polyclonal Antibody (Pab)
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Tested applications
WB, ELISA
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Species reactivity
Human
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Alternative names
Non-receptor tyrosine-protein kinase TNK1 antibody; CD38 negative kinase 1 antibody; TNK1 {ECO:0000312|EMBL:AAC994121} antibody
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Isotype
Rabbit IgG
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Preparation
This TNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 554-588 amino acids from the C-terminal region of human TNK1.
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Clonality
polyclonal
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Storage instructions
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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Applications
WB: 1:1000- 1:2000
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Validations
All lanes : Anti-TNK1 Antibody (C-term) at 1:1000-1:2000 dilution Lane 1: human testis lysates Lane 2: Hela whole cell lysates Lane 3: Jurkat whole cell lysates Lane 4: PC-3 whole cell lysates Lane 5: T47D whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 72 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Background
Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
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References
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"