TIPRL Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
TIP41-like protein antibody; Putative MAPK-activating protein PM10 antibody; Type 2A-interacting protein antibody; TIP antibody; TIPRL antibody
This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human TIPRL.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
TIPRL Antibody (C-term) (Cat. #134833) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TIPRL antibody detected the TIPRL protein (arrow).
May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
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