TIMP3 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
Metalloproteinase inhibitor 3 antibody; Protein MIG-5 antibody; Tissue inhibitor of metalloproteinases 3 antibody; TIMP-3 antibody; TIMP3 antibody
This TIMP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 176-210 amino acids from the C-terminal region of human TIMP3.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Anti-TIMP3 Antibody (C-term) at 1:1000 dilution + human placenta lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
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