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Product Name
Synuclein γ Antibody
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Description
Purified Rabbit Polyclonal Antibody (Pab)
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Tested applications
WB, IHC
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Species reactivity
Human
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Alternative names
BCSG1 antibody; PERSYN antibody; PRSN antibody; Gamma-synuclein antibody; Breast cancer-specific gene 1 protein antibody; Persyn antibody; Synoretin antibody; SR antibody; SNCG antibody; BCSG1 antibody; PERSYN antibody; PRSN antibody
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Isotype
Rabbit IgG
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Clonality
polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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Applications
WB: 1:1000, IHC: 1:50-1:100
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Validations
Western blot analysis of lysate from T47D cell line,using Synuclein γ Antibody(134885). 134885 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
Western blot analysis of extracts from cos-7 cells (Lane 2), using Synuclein γ Antibody. The lane on the left is treated with synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Synuclein γ Antibody .
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Background
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
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References
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"