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Gene name
succinate dehydrogenase complex subunit C
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Organism
Human
- Entrez Gene ID
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Gene Symbol
SDHC
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Gene Type
protein coding
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Also Known as
CYBL; PGL3; QPS1; SDH3; CYB560
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Encoded Protein Alias
succinate dehydrogenase cytochrome b560 subunit, mitochondrial; cytochrome B large subunit of complex II; integral membrane protein CII-3b; succinate dehydrgenase cytochrome b; succinate dehydrogenase 3, integral membrane subunit; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD; succinate-ubiquinone oxidoreductase cytochrome B large subunit
Accession NO.: NM_003001
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Product Name
SDHC(NM_003001) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens succinate dehydrogenase complex subunit C (SDHC), transcript variant 1, mRNA.
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Synonyms
-
ORF length
510
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Annotation
This variant (1) encodes the longest isoform (1).
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siRNA
AGACCAUAAUAGUGGAAAAtt
CAGUUAUUCUCUCUCCAUAtt
GGGAAUCAGAUAGAACUUAtt
GCACUGAUCCACACAGCUAtt
UCAUGUAUCAUACCUGGAAtt
CUGGGAACUUUGAGUCUUAtt
CCUGGAAUGGGAUCCGACAtt
- DataSheet:
- DataSheet:
- DataSheet:
- DataSheet:
- FAQs:
Accession NO.: NM_001035513
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Product Name
SDHC(NM_001035513) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens succinate dehydrogenase complex subunit C (SDHC), transcript variant 4, mRNA.
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Synonyms
-
ORF length
351
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Annotation
This variant (4, also known as delta2+3) lacks two alternate exons in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
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siRNA
AGACCAUAAUAGUGGAAAAtt
CAGUUAUUCUCUCUCCAUAtt
GGGAAUCAGAUAGAACUUAtt
GCACUGAUCCACACAGCUAtt
UCAUGUAUCAUACCUGGAAtt
CUGGGAACUUUGAGUCUUAtt
CCUGGAAUGGGAUCCGACAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001278172
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Product Name
SDHC(NM_001278172) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens succinate dehydrogenase complex subunit C (SDHC), transcript variant 5, mRNA.
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Synonyms
-
ORF length
351
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Annotation
This variant (5, also known as delta 3+5), lacks two alternate exons, which results in a frameshift, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1.
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siRNA
AGACCAUAAUAGUGGAAAAtt
CAGUUAUUCUCUCUCCAUAtt
GGGAAUCAGAUAGAACUUAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001035511
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Product Name
SDHC(NM_001035511) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens succinate dehydrogenase complex subunit C (SDHC), transcript variant 2, mRNA.
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Synonyms
-
ORF length
453
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Annotation
This variant (2, also known as delta5) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
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siRNA
AGACCAUAAUAGUGGAAAAtt
CAGUUAUUCUCUCUCCAUAtt
GGGAAUCAGAUAGAACUUAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001035512
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Product Name
SDHC(NM_001035512) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens succinate dehydrogenase complex subunit C (SDHC), transcript variant 3, mRNA.
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Synonyms
-
ORF length
408
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Annotation
This variant (3, also known as delta3) lacks an alternate exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
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siRNA
AGACCAUAAUAGUGGAAAAtt
CAGUUAUUCUCUCUCCAUAtt
GGGAAUCAGAUAGAACUUAtt
GCACUGAUCCACACAGCUAtt
UCAUGUAUCAUACCUGGAAtt
CUGGGAACUUUGAGUCUUAtt
CCUGGAAUGGGAUCCGACAtt
- DataSheet:
- FAQs:
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Vector Name
pCMV-SPORT6
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primers
T7: TAATACGACTCACTATAGGG
M13 rev: CAGGAAACAGCTATGAC -
Vector Length
4396
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Ampicillin
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Selection Marker
-
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Protein Tag
None
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Description
Vector for cloning and transient mammalian cell expression of cDNAs.
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Vector Name
pEXP-Entry
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primers
T7: TAATACGACTCACTATAGG
M13 rev: CAGGAAACAGCTATGAC -
Vector Length
4919
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Neomycin
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Protein Tag
Myc,FLAG
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Description
ORFs cloned in this vector will be expressed in mammalian cellsas a tagged protein with the C-terminal Myc-FLAG tags.
Such clones are the best for detection and purification of the transgene using anti-Myc or anti-FLAG antibodies.
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Vector Name
pGEM-T
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primers
T7: TAATACGACTCACTATAGGG
M13 rev: CAGGAAACAGCTATGAC -
Vector Length
3000
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Vector Type
Cloning Vector
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Promoter
lac
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Antibiotic Resistance
Ampicillin
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Selection Marker
-
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Protein Tag
None
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Description
The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.
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Vector Name
pOTENT-1
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primers
pOT-F: TAATAGTAATCAATTACGGG
pOT-R: CCTCTACAAATGTGGTATGGC -
Vector Length
7510
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Neomycin
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Protein Tag
FLAG, 6 His
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Description
ORFs cloned in this vector will be expressed in mammalian cells as a tagged protein with the C-terminal FLAG-6 His tags.
Such clones are the best for detection and purification of the transgene using anti-FLAG or anti-His antibodies.
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Vector Name
pcDNA3.1-3xFlag
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
5494
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Ampicillin
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Selection Marker
Neomycin
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Protein Tag
Flag
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Description
Mammalian vector for expressing C-terminal 3xFlag tagged proteins.
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