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  • SARS-CoV-2 Spike S2 ECD-His Protein

SARS-CoV-2 Spike S2 ECD-His Protein

Cat.#: 521013

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Product Information

  • Product Name
    SARS-CoV-2 Spike S2 ECD-His Protein
  • Documents
  • Description
    The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike Protein (S2 ECD) (YP_009724390.1) (Ser686-Pro1213) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    2019-nCoV
  • Molecular weight
    The recombinant SARS-CoV-2 (2019-nCoV) Spike Protein (S2 ECD, His tag) consists of 539 amino acids and predicts a molecular mass of 59.37 kDa.
  • Purity
    >90%
  • Validations

    SARS-CoV-2 Spike S2 ECD-His Protein

    SARS-CoV-2 Spike S2 ECD-His Protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"