-
Gene name
pyruvate kinase, muscle
-
Organism
Human
- Entrez Gene ID
-
Gene Symbol
PKM
-
Gene Type
protein coding
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Also Known as
PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
-
Encoded Protein Alias
pyruvate kinase PKM; OIP-3; OPA-interacting protein 3; PK, muscle type; cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; p58; pyruvate kinase 2/3; pyruvate kinase isozymes M1/M2; pyruvate kinase muscle isozyme; thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tumor M2-PK
Accession NO.: NM_001206798
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Product Name
PKM(NM_001206798) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 6, mRNA.
-
Synonyms
-
ORF length
1551
-
Annotation
This variant (6) differs in the 5' UTR and coding sequence, lacks an alternate exon, and has an alternate in-frame coding exon compared to variant 4. The resulting isoform (e) has a shorter and distinct N-terminus, lacks an alternate internal segment, and has a different internal segment compared to isoform c.
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siRNA
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_002654
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Product Name
PKM(NM_002654) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 1, mRNA.
- Synonyms
-
ORF length
1596
-
Annotation
This variant (1) differs in the 5' UTR and coding sequence and has an alternate in-frame coding exon compared to variant 4. The resulting isoform (a, also called M2) is shorter at the N-terminus and has a different internal segment compared to isoform c.
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siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
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- FAQs:
Accession NO.: XM_006720570
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Product Name
PKM(XM_006720570) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens pyruvate kinase, muscle (PKM), transcript variant X1, mRNA.
-
Synonyms
-
ORF length
1818
-
siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: XM_005254443
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Product Name
PKM(XM_005254443) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens pyruvate kinase, muscle (PKM), transcript variant X2, mRNA.
-
Synonyms
-
ORF length
1776
-
siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001316318
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Product Name
PKM(NM_001316318) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 8, mRNA.
- Synonyms
-
ORF length
1701
-
Annotation
This variant (8) lacks an alternate in-frame exon in the 5' end of the coding sequence compared to variant 4. The resulting isoform (g) has the same N- and C-termini but is shorter compared to isoform c.
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siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001206799
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Product Name
PKM(NM_001206799) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 7, mRNA.
-
Synonyms
-
ORF length
1611
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Annotation
This variant (7) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (f) has a shorter and distinct N-terminus compared to isoform c.
-
siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001206796
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Product Name
PKM(NM_001206796) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 4, mRNA.
-
Synonyms
-
ORF length
1818
-
Annotation
This variant (4) represents the longest transcript and encodes the longest isoform (c).
-
siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_182471
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Product Name
PKM(NM_182471) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 2, mRNA.
- Synonyms
-
ORF length
1596
-
Annotation
This variant (2) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (b, also called M1) is shorter at the N-terminus compared to isoform c.
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siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- DataSheet:
- FAQs:
Accession NO.: XM_011521670
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Product Name
PKM(XM_011521670) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens pyruvate kinase, muscle (PKM), transcript variant X3, mRNA.
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Synonyms
-
ORF length
1701
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siRNA
GAUUAAGUCUGGAAUGAAUtt
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001206797
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Product Name
PKM(NM_001206797) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 5, mRNA.
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Synonyms
-
ORF length
1374
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Annotation
This variant (5) differs in the 5' UTR and coding sequence, lacks an alternate in-frame segment, and has an alternate in-frame coding exon compared to variant 4. The resulting isoform (d) is shorter at the N-terminus, lacks an alternate internal segment, and has a different internal segment compared to isoform c.
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siRNA
CAUCAAGAUUAUCAGCAAAtt
GGAAAGAACAUCAAGAUUAtt
GCAUUGAGAUUCCUGCAGAtt
- DataSheet:
- FAQs:
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Vector Name
pEXP-C-EGFP
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6703
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Hygromycin
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Protein Tag
GFPSpark
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-FLAG
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6013
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
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Protein Tag
FLAG
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-HA
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6016
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Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
HA
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-His
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6019
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
His
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-Myc
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6019
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Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
Myc
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-mOrange2
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6662
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
OFPSpark
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-N-FLAG
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6013
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
FLAG
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-N-HA
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6016
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
HA
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
-
Vector Name
pEXP-N-His
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6019
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
His
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
-
Vector Name
pEXP-N-Myc
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6019
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
Myc
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
-
Vector Name
pEXP-N-mOrange2
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6662
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
OFPSpark
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
-
Vector Name
pEXP-untagged
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6223
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Ampicillin
-
Selection Marker
Hygromycin
-
Protein Tag
None
-
Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
-
Vector Name
pUC18c
-
primers
M13 fwd: GTAAAACGACGGCCAGT
M13 rev: CAGGAAACAGCTATGAC -
Vector Length
2693
-
Vector Type
Cloning Vector
-
Promoter
lac
-
Antibiotic Resistance
Ampicillin
-
Selection Marker
-
-
Protein Tag
None
-
Description
pMD18-T Vector is a high-efficiency TA cloning vector constructed from pUC18, of which the initial multiple cloning sites (MCS) were destroyed. Thus the cDNA should be amplified by PCR with primers containing a restriction site for subclone. Competent cells appropriate for pUC18 are also appropriated for this Vector, e.g. JM109, DH5α, TOP10. The pMD18-T Simple Vector is 2.6kb in size. Selection of the plasmid in E. coli is conferred by the ampicillin resistance gene. The coding sequence was inserted by TA cloning at site 425.
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Vector Name
pcDNA3.1-3xFlag
-
primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
5494
-
Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Ampicillin
-
Selection Marker
Neomycin
-
Protein Tag
Flag
-
Description
Mammalian vector for expressing C-terminal 3xFlag tagged proteins.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"