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Product Name
PYCR2 Antibody (Center)
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Description
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Tested applications
WB, IHC-P, ELISA
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Species reactivity
Human
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Alternative names
Pyrroline-5-carboxylate reductase 2 antibody; P5C reductase 2 antibody; P5CR 2 antibody; PYCR2 antibody
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Isotype
Rabbit IgG
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Preparation
This PYCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human PYCR2.
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Clonality
Polyclonal
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Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage instructions
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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Applications
WB: 1:1000, IHC-P: 1:10~50
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Validations
PYCR2 Antibody (Center) (Cat. #137349) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PYCR2 antibody detected the PYCR2 protein (arrow).
PYCR2 Antibody (Center) (Cat. #137349)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PYCR2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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Background
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH.
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References
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"