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  • Phospho-PTPN6-Y564 pAb

Phospho-PTPN6-Y564 pAb

Cat.#: 166517

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Product Information

  • Product Name
    Phospho-PTPN6-Y564 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-PTPN6-Y564
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    PTPN6 antibody; HCP antibody; HCPH antibody; HPTP1C antibody; PTP-1C antibody; SH-PTP1 antibody; SHP-1 antibody; SHP-1L antibody; SHP1 antibody; tyrosine-protein phosphatase non-receptor type 6 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic phosphorylated peptide around Y564 of human PTPN6 (NP_002822.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - Phospho-PTPN6-Y564 pAb

    Western blot - Phospho-PTPN6-Y564 pAb

    Western blot analysis of extracts of HeLa and RAW 264.7 cells, using Phospho-PTPN6-Y564 antibody at 1:2000 dilution. HeLa cell lysates were treated by CIP at 37u00b0C for 1 hour.RAW 264.7 cell lysates were treated by CIP at 37u00b0C for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Enhanced Kit .Exposure time: 3min.

  • Background
    Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"