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  • Phospho-PTPN6-Y536 pAb
  • Phospho-PTPN6-Y536 pAb

Phospho-PTPN6-Y536 pAb

Cat.#: 166448

Special Price 232.3 USD

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Product Information

  • Product Name
    Phospho-PTPN6-Y536 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-PTPN6-Y536
  • Tested applications
    IHC, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    PTPN6 antibody; HCP antibody; HCPH antibody; HPTP1C antibody; PTP-1C antibody; SH-PTP1 antibody; SHP-1 antibody; SHP-1L antibody; SHP1 antibody; tyrosine-protein phosphatase non-receptor type 6 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A phospho specific peptide corresponding to residues surrounding Y536 of human PTPN6
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    IHC 1:50 - 1:100
    IF 1:100 - 1:200
  • Validations

    Immunohistochemistry - Phospho-PTPN6-Y536 pAb

    Immunohistochemistry - Phospho-PTPN6-Y536 pAb

    Immunohistochemistry of paraffin-embedded human breast carcinoma tissue, using Phospho-PTPN6-Y536 antibody .

    Immunofluorescence - Phospho-PTPN6-Y536 pAb

    Immunofluorescence - Phospho-PTPN6-Y536 pAb

    Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-PTPN6-Y536 antibody .

  • Background
    Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"