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  • Phospho-MEF2A-T319 pAb

Phospho-MEF2A-T319 pAb

Cat.#: 166434

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Product Information

  • Product Name
    Phospho-MEF2A-T319 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-MEF2A-T319
  • Tested applications
    IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    MEF2A antibody; ADCAD1 antibody; RSRFC4 antibody; RSRFC9 antibody; mef2 antibody; myocyte enhancer factor 2A antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A phospho specific peptide corresponding to residues surrounding T319 of human MEF2A
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    IF 1:100 - 1:200
  • Validations

    Immunofluorescence - Phospho-MEF2A-T319 pAb

    Immunofluorescence - Phospho-MEF2A-T319 pAb

    Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-MEF2A-T319 antibody .

  • Background
    Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"