Polyclonal antibody to Phospho-GJA1-S368
Human, Mouse, Rat
GJA1 antibody; AVSD3 antibody; CMDR antibody; CX43 antibody; EKVP antibody; GJAL antibody; HLHS1 antibody; HSS antibody; ODDD antibody; PPKCA antibody; EKVP3 antibody; gap junction alpha-1 protein antibody
Antigen: A phospho specific peptide corresponding to residues surrounding S368 of human GJA1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Western blot - Phospho-GJA1-S368 pAb
Western blot analysis of extracts from 293 cells, using Phospho-GJA1-S368 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.
Immunohistochemistry - Phospho-GJA1-S368 pAb
Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-GJA1-S368 antibody .
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
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