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  • Phospho-GJA1-S368 pAb
  • Phospho-GJA1-S368 pAb

Phospho-GJA1-S368 pAb

Cat.#: 166410

Special Price 232.3 USD

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Product Information

  • Product Name
    Phospho-GJA1-S368 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-GJA1-S368
  • Tested applications
    WB, IHC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    GJA1 antibody; AVSD3 antibody; CMDR antibody; CX43 antibody; EKVP antibody; GJAL antibody; HLHS1 antibody; HSS antibody; ODDD antibody; PPKCA antibody; EKVP3 antibody; gap junction alpha-1 protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A phospho specific peptide corresponding to residues surrounding S368 of human GJA1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:100
  • Validations

    Western blot - Phospho-GJA1-S368 pAb

    Western blot - Phospho-GJA1-S368 pAb

    Western blot analysis of extracts from 293 cells, using Phospho-GJA1-S368 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.

    Immunohistochemistry - Phospho-GJA1-S368 pAb

    Immunohistochemistry - Phospho-GJA1-S368 pAb

    Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-GJA1-S368 antibody .

  • Background
    Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"