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  • Phospho-c-Jun-T239 pAb

Phospho-c-Jun-T239 pAb

Cat.#: 166418

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Product Information

  • Product Name
    Phospho-c-Jun-T239 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-c-Jun-T239
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    JUN antibody; AP-1 antibody; AP1 antibody; c-Jun antibody; transcription factor AP-1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A phospho specific peptide corresponding to residues surrounding T239 of human c-Jun
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - Phospho-c-Jun-T239 pAb

    Western blot - Phospho-c-Jun-T239 pAb

    Western blot analysis of extracts from HeLa cells, using Phospho-c-Jun-T239 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.

  • Background
    Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"