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Product Name
Phospho-BCL2L11-S69 pAb
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Description
Polyclonal antibody to Phospho-BCL2L11-S69
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Tested applications
IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
BCL2L11 antibody; BAM antibody; BIM antibody; BOD antibody; BCL2 like 11 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A phospho specific peptide corresponding to residues surrounding S69 of human BCL2L11
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:100
IF 1:100 - 1:200 -
Validations
Immunohistochemistry - Phospho-BCL2L11-S69 pAb
Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-BCL2L11-S69 antibody .
Immunofluorescence - Phospho-BCL2L11-S69 pAb
Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-BCL2L11-S69 antibody .
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Background
Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
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References
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"