Purified Mouse Monoclonal Antibody (Mab)
EDR antibody; KIAA1051 antibody; MAR2 antibody; MART2 antibody; MEF3L1 antibody; RGAG antibody; AA407948;Edr;Embryonal carcinoma differentiation regulated;Embryonal carcinoma differentiation-regulated protein;HB 1;HB1;KIAA1051;Mammalian retrotransposon-derived protein 2;Mar2;Mart2;MEF3 like 1;MEF3-like protein 1;MEF3L;MEF3L1;MyEF 3;Myelin expression factor 3-like protein 1;Paternally expressed 10;Paternally expressed gene 10 ORF1;Paternally expressed gene 10 protein;Peg10;PEG10 protein;PEG10_HUMAN;Putative uncharacterized protein PEG10;Retrotransposon gag domain containing 3;Retrotransposon gag domain-containing protein 3;Retrotransposon-derived gag-like polyprotein; Retrotransposon-derived protein PEG10;RGAG3;Ty3/Gypsy-like protein. antibody
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
WB: 1:1000, IP: 1:500
Western blot detection of PEG10 in Hela cell lysates using PEG10 mouse mAb (1:1000 diluted).Predicted band size:55KDa.Observed band size:55KDa,95KDa.
Immunoprecipitation analysis of Hela cell lysates using PEG10 mouse mAb.
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"