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  • Human SUMO1 Recombinant protein (GST tag)

Human SUMO1 Recombinant protein (GST tag)

Cat.#: 513335

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Product Information

  • Product Name
    Human SUMO1 Recombinant protein (GST tag)
  • Documents
  • Description
    Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
  • Protein name
    Small ubiquitin-related modifier 1
  • Protein short names
    SMT3H3; DAP1; MGC103203; SUMO1; SUMO-1; SMT3C; GMP1; OK/SW-CL.43; SMT3; SMTP3; OFC10; SENTRIN; SENP2; PIC1; UBL1
  • Uniprot ID
    P63165
  • Gene Name
    SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-101 aa encoded by BC006462 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human SUMO1 SDS-PAGE

    Recombinant human SUMO1 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"