Human RFK Recombinant protein (GST tag)
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Protein short names
AF031381; RP11-422N19.2; 0610038L10RIK; KOI-4; FLAVOKINASE; ATP:RIBOFLAVIN 5'-PHOSPHOTRANSFERASE; RIFK
1-162 aa encoded by BC007069 was inserted into PGEX-4T vector
Recombinant human RFK SDS-PAGE
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