• Human PKM Recombinant protein (His tag)

Human PKM Recombinant protein (His tag)

Cat.#: 511286

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Product Information

  • Product Name
    Human PKM Recombinant protein (His tag)
  • Documents
  • Description
    Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
  • Protein name
    Pyruvate kinase PKM
  • Protein short names
    CTHBP; THBP1; AL024370; AL024424; PK-2; HEL-S-30; MGC3932; OIP3; AA414905; TCB; PKM2; PKM; PK3; PK-3
  • Uniprot ID
    P14618
  • Gene Name
    PKM; OIP3; PK2; PK3; PKM2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-531 aa encoded by NM_002654 was inserted into PET28a vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human PKM SDS-PAGE

    Recombinant human PKM SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"