Human MAD2L1 Recombinant protein (His tag)
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Mitotic spindle assembly checkpoint protein MAD2A
Protein short names
HSMAD2; MAD2; MGC113763; AA673185; MAD2L1
16-185 aa encoded by NM_002358 was inserted into PET28a vector
Recombinant human MAD2L1 SDS-PAGE
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