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Product Name
Human MAD2L1 Recombinant protein (His tag)
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Description
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
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Protein name
Mitotic spindle assembly checkpoint protein MAD2A
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Protein short names
HSMAD2; MAD2; MGC113763; AA673185; MAD2L1
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Uniprot ID
Q13257
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Gene Name
MAD2L1; MAD2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
16-185 aa encoded by NM_002358 was inserted into PET28a vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human MAD2L1 SDS-PAGE
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