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Gene name
estrogen receptor 1
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Organism
Human
- Entrez Gene ID
-
Gene Symbol
ESR1
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Gene Type
protein coding
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Also Known as
ER; ESR; Era; ESRA; ESTRR; NR3A1
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Encoded Protein Alias
estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1
Accession NO.: XM_006715374
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Product Name
ESR1(XM_006715374) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X11, mRNA.
-
Synonyms
-
ORF length
1401
-
siRNA
ACAUCAUCUCGGUUCCGCAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: XM_006715375
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Product Name
ESR1(XM_006715375) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X12, mRNA.
-
Synonyms
-
ORF length
1269
-
siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001291241
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Product Name
ESR1(NM_001291241) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens estrogen receptor 1 (ESR1), transcript variant 6, mRNA.
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Synonyms
-
ORF length
1785
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Annotation
This variant (6) differs in the 5' UTR and has an alternate splice site in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal aa in the N-terminal region, compared to isoform 1.
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: XM_011535549
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Product Name
ESR1(XM_011535549) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X16, mRNA.
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Synonyms
-
ORF length
1059
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_000125
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Product Name
ESR1(NM_000125) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA.
- Synonyms
-
ORF length
1788
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Annotation
This variant (1) uses the most proximal promoter, and encodes isoform 1. Variants 1-4 all encode the same isoform 1.
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
- DataSheet:
- FAQs:
Accession NO.: XM_011535547
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Product Name
ESR1(XM_011535547) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X10, mRNA.
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Synonyms
-
ORF length
1452
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: XM_017010383
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Product Name
ESR1(XM_017010383) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X17, mRNA.
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Synonyms
-
ORF length
999
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001328100
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Product Name
ESR1(NM_001328100) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens estrogen receptor 1 (ESR1), transcript variant 7, mRNA.
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Synonyms
-
ORF length
933
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Annotation
This variant (7) differs in the both UTRs, has a shorter 5' coding region and differs in the 3' coding region compared to variant 1. The encoded isoform (4) is shorter at the n-terminus and has a distinct C-terminus compared to isoform 1.
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: NM_001291230
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Product Name
ESR1(NM_001291230) Human cDNA/ORF Clone
- Accession NO.
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Transcript Name
Homo sapiens estrogen receptor 1 (ESR1), transcript variant 5, mRNA.
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Synonyms
-
ORF length
1794
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Annotation
This variant (5) differs in the 5' UTR and has an alternate splice site in the 5' coding region, compared to variant 1. The resulting isoform (2) has additional two amino acids in the N-terminal region, compared to isoform 1.
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
Accession NO.: XM_017010382
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Product Name
ESR1(XM_017010382) Human cDNA/ORF Clone
- Accession NO.
-
Transcript Name
PREDICTED: Homo sapiens estrogen receptor 1 (ESR1), transcript variant X13, mRNA.
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Synonyms
-
ORF length
1131
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siRNA
ACAUCAUCUCGGUUCCGCAtt
CAGGCACAUGAGUAACAAAtt
CGAGUAUGAUCCUACCAGAtt
- DataSheet:
- FAQs:
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Vector Name
pEXP-C-EGFP
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6703
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Hygromycin
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Protein Tag
GFPSpark
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-FLAG
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6013
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Hygromycin
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Protein Tag
FLAG
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-C-mOrange2
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6662
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Hygromycin
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Protein Tag
OFPSpark
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-N-EGFP
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6703
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
-
Protein Tag
GFPSpark
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-N-FLAG
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6013
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Vector Type
Mammalian Expression Vector
-
Promoter
CMV
-
Antibiotic Resistance
Kanamycin
-
Selection Marker
Hygromycin
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Protein Tag
FLAG
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-N-HA
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6016
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Hygromycin
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Protein Tag
HA
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pEXP-untagged
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
6223
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Ampicillin
-
Selection Marker
Hygromycin
-
Protein Tag
None
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Description
All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
• Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
• Hygromycin resistance gene for selection of mammalian cell lines.
• A Kozak consensus sequence to enhance mammalian expression.
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Vector Name
pGEM-T
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primers
T7: TAATACGACTCACTATAGGG
M13 rev: CAGGAAACAGCTATGAC -
Vector Length
3000
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Vector Type
Cloning Vector
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Promoter
lac
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Antibiotic Resistance
Ampicillin
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Selection Marker
-
-
Protein Tag
None
-
Description
The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.
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Vector Name
pOTENT-1
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primers
pOT-F: TAATAGTAATCAATTACGGG
pOT-R: CCTCTACAAATGTGGTATGGC -
Vector Length
7510
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Kanamycin
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Selection Marker
Neomycin
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Protein Tag
FLAG, 6 His
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Description
ORFs cloned in this vector will be expressed in mammalian cells as a tagged protein with the C-terminal FLAG-6 His tags.
Such clones are the best for detection and purification of the transgene using anti-FLAG or anti-His antibodies.
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Vector Name
pcDNA3.1-3xFlag
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primers
T7: TAATACGACTCACTATAGGG
BGH: TAGAAGGCACAGTCGAGG -
Vector Length
5508
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Vector Type
Mammalian Expression Vector
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Promoter
CMV
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Antibiotic Resistance
Ampicillin
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Selection Marker
Neomycin
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Protein Tag
Flag
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Description
Mammalian vector for expressing C-terminal 3xFlag tagged proteins.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"