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Product Name
DOK7 Antibody (N-term)
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Description
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Tested applications
WB, ELISA
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Species reactivity
Mouse
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Alternative names
C4orf25 antibody; Protein Dok-7 antibody; Downstream of tyrosine kinase 7 antibody; DOK7 antibody; C4orf25 antibody
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Isotype
Rabbit IgG
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Preparation
This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.
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Clonality
Polyclonal
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Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage instructions
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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Applications
WB: 1:1000
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Validations
DOK7 Antibody (N-term) (Cat. #137120) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the DOK7 antibody detected the DOK7 protein (arrow).
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Background
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
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References
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"