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  • DEF6 Antibody (C-term)

DEF6 Antibody (C-term)

Cat.#: 134868

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Special Price 372.6 USD

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Product Information

  • Product Name
    DEF6 Antibody (C-term)
  • Documents
  • Description
    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
  • Tested applications
    WB, ELISA
  • Species reactivity
    Human
  • Alternative names
    IBP antibody; Differentially expressed in FDCP 6 homolog antibody; DEF-6 antibody; IRF4-binding protein antibody; DEF6 antibody; IBP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.
  • Clonality
    Polyclonal
  • Formulation
    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Storage instructions
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
  • Applications
    WB: 1:1000
  • Validations

    DEF6 Antibody (C-term) (Cat. #134868) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the DEF6 antibody detected the DEF6 protein (arrow).

    DEF6 Antibody (C-term) (Cat. #134868) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the DEF6 antibody detected the DEF6 protein (arrow).

  • Background
    Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"