DEF6 Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
IBP antibody; Differentially expressed in FDCP 6 homolog antibody; DEF-6 antibody; IRF4-binding protein antibody; DEF6 antibody; IBP antibody
This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
DEF6 Antibody (C-term) (Cat. #134868) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the DEF6 antibody detected the DEF6 protein (arrow).
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
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