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  • CXCL16 antibody
  • CXCL16 antibody
  • CXCL16 antibody
  • CXCL16 antibody

CXCL16 antibody

Cat.#: 109640

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Special Price 239.0 USD

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Product Information

  • Product Name
    CXCL16 antibody
  • Documents
  • Description
    CXCL16 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Positive IHC detected in human prostate cancer tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 35 kDa
  • Tested applications
    ELISA, IF, IHC, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    C X C motif chemokine 16 antibody; CXCL16 antibody; CXCLG16 antibody; SCYB16 antibody; Small inducible cytokine B16 antibody; SR PSOX antibody; SRPSOX antibody; Transmembrane chemokine CXCL16 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CXCL16 recombinant protein (Accession Number: BC017588). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:50-1:500

    IF: 1:50-1:500

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:109640(CXCL16 Antibody) at dilution of 1:600

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:109640(CXCL16 Antibody) at dilution of 1:600

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109640(CXCL16 Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109640(CXCL16 Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109640(CXCL16 Antibody) at dilution of 1:200 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:109640(CXCL16 Antibody) at dilution of 1:200 (under 40x lens).

    Immunofluorescent analysis of (-20oc Ethanol) fixed HeLa cells using Catalog No:109640(CXCL16 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed HeLa cells using Catalog No:109640(CXCL16 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"