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  • CASP8 Human cDNA/ORF Clone

CASP8 Human cDNA/ORF Clone

Cat.#: 714598-1

  • Accession#:
  • Vector:
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Product Information

  • Gene name
    caspase 8
  • Organism
    Human
  • Entrez Gene ID
    841
  • Gene Symbol
    CASP8
  • Gene Type
    protein coding
  • Also Known as
    CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
  • Encoded Protein Alias
    caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; ICE-like apoptotic protease 5; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MORT1-associated ced-3 homolog; apoptotic cysteine protease; apoptotic protease Mch-5; caspase 8, apoptosis-related cysteine protease
  • Product Name
    CASP8(NM_033358) Human cDNA/ORF Clone
  • Accession NO.
    NM_033358
  • Transcript Name
    Homo sapiens caspase 8 (CASP8), transcript variant E, mRNA.
  • Synonyms
    XM_006712793  
  • ORF length
    708
  • Annotation
    This variant (E), also known as Beta-1, has multiple differences, one of which causes a frameshift, compared to variant G. It encodes isoform E, which is shorter than isoform G.
  • siRNA

    GAUAAUCAACGACUAUGAAtt

    GAUCAGAAUUGAGGUCUUUtt

    GAUACUGUCUGAUCAUCAAtt

  • DataSheet:
    NM_033358 in pcDNA3.1-3xFlag
  • FAQs:
    DNA products or services FAQs
  • Product Name
    CASP8(NM_033356) Human cDNA/ORF Clone
  • Accession NO.
    NM_033356
  • Transcript Name
    Homo sapiens caspase 8 (CASP8), transcript variant F, mRNA.
  • Synonyms
    XM_005246892   NM_001080124  
  • ORF length
    1395
  • Annotation
    This variant (F) includes different segments in the 5' UTR and lacks an alternate in-frame segment in the coding region, compared to variant G. Variants C and F both encode isoform C, which is shorter than isoform G. Isoform C has also been labelled as Alpha-2 or MCH5-beta.
  • siRNA

    GAUAAUCAACGACUAUGAAtt

    GAUCAGAAUUGAGGUCUUUtt

    GAUACUGUCUGAUCAUCAAtt

  • DataSheet:
    NM_033356 in pOTENT-1
  • FAQs:
    DNA products or services FAQs
  • Product Name
    CASP8(NM_001080125) Human cDNA/ORF Clone
  • Accession NO.
    NM_001080125
  • Transcript Name
    Homo sapiens caspase 8 (CASP8), transcript variant G, mRNA.
  • Synonyms
  • ORF length
    1617
  • Annotation
    This variant (G), also known as procaspase-8L or 8L, encodes the longest protein (isoform G).
  • siRNA

    GAUAAUCAACGACUAUGAAtt

    GAUCAGAAUUGAGGUCUUUtt

    GAUACUGUCUGAUCAUCAAtt

  • DataSheet:
    NM_001080125 in pcDNA3.1-3xFlag
  • FAQs:
    DNA products or services FAQs
  • Product Name
    CASP8(NM_001228) Human cDNA/ORF Clone
  • Accession NO.
    NM_001228
  • Transcript Name
    Homo sapiens caspase 8 (CASP8), transcript variant A, mRNA.
  • Synonyms
  • ORF length
    1491
  • Annotation
    This variant (A), also known as Alpha-4, has multiple differences in the 5' UTR and coding region, compared to variant G. It encodes isoform A which is shorter than isoform G.
  • siRNA

    GAUAAUCAACGACUAUGAAtt

    GAUCAGAAUUGAGGUCUUUtt

    GAUACUGUCUGAUCAUCAAtt

  • DataSheet:
    NM_001228 in pcDNA3.1-3xFlag
  • FAQs:
    DNA products or services FAQs
  • Vector Name
    pEXP-C-EGFP
  • primers
    T7: TAATACGACTCACTATAGGG
    BGH: TAGAAGGCACAGTCGAGG
  • Vector Length
    6703
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Kanamycin
  • Selection Marker
    Hygromycin
  • Protein Tag
    GFPSpark
  • Description
    All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
    • Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
    • Hygromycin resistance gene for selection of mammalian cell lines.
    • A Kozak consensus sequence to enhance mammalian expression.
  • Vector Name
    pEXP-C-FLAG
  • primers
    T7: TAATACGACTCACTATAGGG
    BGH: TAGAAGGCACAGTCGAGG
  • Vector Length
    6013
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Kanamycin
  • Selection Marker
    Hygromycin
  • Protein Tag
    FLAG
  • Description
    All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
    • Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
    • Hygromycin resistance gene for selection of mammalian cell lines.
    • A Kozak consensus sequence to enhance mammalian expression.
  • Vector Name
    pEXP-C-mOrange2
  • primers
    T7: TAATACGACTCACTATAGGG
    BGH: TAGAAGGCACAGTCGAGG
  • Vector Length
    6662
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Kanamycin
  • Selection Marker
    Hygromycin
  • Protein Tag
    OFPSpark
  • Description
    All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
    • Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
    • Hygromycin resistance gene for selection of mammalian cell lines.
    • A Kozak consensus sequence to enhance mammalian expression.
  • Vector Name
    pEXP-N-FLAG
  • primers
    T7: TAATACGACTCACTATAGGG
    BGH: TAGAAGGCACAGTCGAGG
  • Vector Length
    6013
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Kanamycin
  • Selection Marker
    Hygromycin
  • Protein Tag
    FLAG
  • Description
    All of the pEXP vectors are designed for high-level stable and transient expression in mammalian hosts. High-level stable and non-replicative transient expression can be carried out in most mammalian cells. The vectors contain the following elements:
    • Human enhanced cytomegalovirus immediate-early (CMV) promoter for high-level expression in a wide range of mammalian cells.
    • Hygromycin resistance gene for selection of mammalian cell lines.
    • A Kozak consensus sequence to enhance mammalian expression.
  • Vector Name
    pOTENT-1
  • primers
    pOT-F: TAATAGTAATCAATTACGGG
    pOT-R: CCTCTACAAATGTGGTATGGC
  • Vector Length
    7510
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Kanamycin
  • Selection Marker
    Neomycin
  • Protein Tag
    FLAG, 6 His
  • Description
    ORFs cloned in this vector will be expressed in mammalian cells as a tagged protein with the C-terminal FLAG-6 His tags.
    Such clones are the best for detection and purification of the transgene using anti-FLAG or anti-His antibodies.
  • Vector Name
    pUC18c
  • primers
    M13 fwd: GTAAAACGACGGCCAGT
    M13 rev: CAGGAAACAGCTATGAC
  • Vector Length
    2693
  • Vector Type
    Cloning Vector
  • Promoter
    lac
  • Antibiotic Resistance
    Ampicillin
  • Selection Marker
    -
  • Protein Tag
    None
  • Description
    pMD18-T Vector is a high-efficiency TA cloning vector constructed from pUC18, of which the initial multiple cloning sites (MCS) were destroyed. Thus the cDNA should be amplified by PCR with primers containing a restriction site for subclone. Competent cells appropriate for pUC18 are also appropriated for this Vector, e.g. JM109, DH5α, TOP10. The pMD18-T Simple Vector is 2.6kb in size. Selection of the plasmid in E. coli is conferred by the ampicillin resistance gene. The coding sequence was inserted by TA cloning at site 425.
  • Vector Name
    pcDNA3.1-3xFlag
  • primers
    T7: TAATACGACTCACTATAGGG
    BGH: TAGAAGGCACAGTCGAGG
  • Vector Length
    5508
  • Vector Type
    Mammalian Expression Vector
  • Promoter
    CMV
  • Antibiotic Resistance
    Ampicillin
  • Selection Marker
    Neomycin
  • Protein Tag
    Flag
  • Description
    Mammalian vector for expressing C-terminal 3xFlag tagged proteins.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"