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  • Anti-Spike-RBD Human mAb

Anti-Spike-RBD Human mAb

Cat.#: 166656

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Special Price 261.0 USD

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Product Information

  • Product Name
    Anti-Spike-RBD Human mAb
  • Documents
  • Description
    human monoclonal antibody against Spike protein receptor binding domain
  • Tested applications
    ELISA
  • Species reactivity
    Human
  • Isotype
    Human IgG
  • Clonality
    Monoclonal
  • Formulation
    PBS(pH7.2)
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    Paired antibodies to detect SARS-COV-2 S-RBD using the double-antibody sandwich method with antibody(Cat#: 166655)
  • Validations

    Double antibody sandwich Elisa usering two anti-S1-RBD antibodies and S1 protein

    Double antibody sandwich Elisa usering two anti-S1-RBD antibodies and S1 protein

    The two anti-S1-RBD human monoclonal antibodies(Cat#: 166655 and 166656) can simultaneously and stably bind to different epitopes of the SARS-COV-2 S1-RBD protein, with an EC50 value of 0.23 nM. The affinity of this antibody binding to RBD is 0.56 nM (ELISA)

  • Background
    The S protein of the SARS-COV-2 binds to the receptor of ACE2 protein on cell membrane, and then infects human respiratory epithelial cells. The observation under electron microscope confirmed the molecular mechanism of the infection. The specific binding to the receptor of ACE2 molecule is the receptor binding domain (RBD)located on the S1 Subunit of the S protein.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"