Anti-TNFRSF11B antibody

Cat.#: 176717

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Product Information

  • Product Name
    Anti-TNFRSF11B antibody
  • Documents
  • Description
    Rabbit polyclonal antibody to TNFRSF11B
  • Tested applications
    WB, ICC, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    OPG antibody; TR1 antibody; OCIF antibody; PDB5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antigen of this antibody was recombinant protein within human osteoprotegerin aa 22-232.
  • Clonality
    Polyclonal
  • Formulation
    Liquid, 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Applications

    WB: 1:500-1:2,000

    ICC: 1:100-1:500

    IHC-P: 1:50-1:200

  • Validations

    Fig1: Western blot analysis of Osteoprotegerin on 293 (1) and K562 (2) cell lysate using anti-Osteoprotegerin antibody at 1/500 dilution.

    Fig1: Western blot analysis of Osteoprotegerin on 293 (1) and K562 (2) cell lysate using anti-Osteoprotegerin antibody at 1/500 dilution.

    Fig2: ICC staining Osteoprotegerin in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining Osteoprotegerin in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig6: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig7: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

    Fig7: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-Osteoprotegerin antibody. Counter stained with hematoxylin.

  • Background
  • References
    • Bao Y et al. Topical Treatment with Xiaozheng Zhitong Paste (XZP) Alleviates Bone Destruction and Bone Cancer Pain in a Rat Model of Prostate Cancer-Induced Bone Pain by Modulating the RANKL/RANK/OPG Signaling. Evid Based Complement Alternat Med 2015:215892 (2015).
    • Peng X et al. Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer. PLoS One 8:e58361 (2013).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"